Bills vs. Lions predictions, odds, spread, time: Week 2 'Thursday Night Football' picks from proven model

SportsLine has released predictions and betting odds for the NFL Week 2 game between the Buffalo Bills and Detroit Lions on September 17. The game will be held at Highmark Stadium. This matchup serves as the stadium's first regular-season game of the year.
The SportsLine projection model has revealed its Detroit vs. Buffalo picks for NFL Week 2 on Thursday, Sept. 17 as Highmark Stadium hosts its first regular-season game
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